Henry Corden

Fred Flintstone / Monkey #2 / Turtle #2 (voice)

Mel Blanc

Barney Rubble (voice)

Jean Vander Pyl

Wilma Flintstone / Pebbles Flintstone / Elephant (voice)

Gay Autterson

Betty Rubble / Nurse / Turtle #1 (voice)

John Stephenson

Frank Frankenstone / Dinosaur / Monkey #1 (voice)

Don Messick

Doctor / Fish #1 / Fish #2 / Parrot / Pigasaurus (voice)